New York Yankees vs Chicago White Sox April 30, 2010

In 2004, the Yankees acquired Alex Rodriguez, who moved to third base from his usual shortstop position to accommodate Derek Jeter. In the ALCS, the Yankees met the Boston Red Sox again, and became the first team in professional baseball history, and only the third team in North American pro sports history, to lose a best-of-seven series after taking a 3–0 series lead.