ATS 2010 International Conference May 13, 2010

Poster by J. Parker, Director, Clinical Development, C. Le, B.White and N. Molfino on the topic of randomized, double-blind, placebo-controlled, multicenter study to evaluate the effect of a humanized interleukin-9 monoclonal antibody (MEDI-528) on exercise-induced bronchospasm.

Abstract by Rajesh Narwal, Scientist I, Gabriel Robbie and Lorin Roskos on semi-mechanistic pharmacokinetic-pharmacodynamic modeling of MEDI 575 in solid tumor patients.

Poster by DK Finch, Principal Scientist, MA Sleeman, Piper, Dubmore, Coyla and Anderson on the topic on interleukin-I mediated responses to rhinoviral infection an dincreased susceptibility of epiethelial cells to rhinovirus.

Poster by Ian Strickland, Scientist II on the preclinical development of MEDI 2045 an IL-4R- neutralising antibody for the treatment of severe uncontrolled asthma.

Poster by Matthew Robinson, Scientist II, I Strickland, AJ Coyle, MA Sleeman, IK Anderson and RD May on the thymic stromal lymphopoeitin (TSLP) activates human and cynomolgus macaque dendritic cells and induces Th1 as well as Th2 responses in human total T helper cells.

Poster by Kimmie McLaurin, Senior Manager on cost comparison among moderate or severe persistent asthma patients.

Poster by Suzanne Cohen, Maria Lindahl, Amir Smailagic, Marie Hornfelt, Laura Eghobamien, Jamie Campbell, Ian Anderson, Anthony Coyle and Matthew Steeman on LPS-induced lung inglammation in Mic is inhibited by antibody antagonists of the GM-CSF receptor.